Shanghai Orsin Medical Technology Co., Ltd. miaomiao8615@orsins.com 86-021-57450666
Product Details
Place of Origin: China
Brand Name: Orsin
Payment & Shipping Terms
Minimum Order Quantity: 100
Price: Negotiation
Payment Terms: L/C, D/A, D/P, T/T, Western Union
Color: |
Purple |
Application: |
Early Disease Detection |
Material: |
Glass And Pet |
Advantage: |
Sterile And Safe Compatible With Equipment |
Trait: |
Cancer |
Capacity: |
10ml |
Color: |
Purple |
Application: |
Early Disease Detection |
Material: |
Glass And Pet |
Advantage: |
Sterile And Safe Compatible With Equipment |
Trait: |
Cancer |
Capacity: |
10ml |
Orsin Medical Technology – Cell-Free DNA (cfDNA) Extraction & Analysis Solutions
1. Product Description
Orsin Medical Technology delivers high-efficiency, ultra-sensitive cfDNA extraction and detection products, designed for liquid biopsy, non-invasive prenatal testing (NIPT), cancer early screening, and transplant monitoring.
Key Advantages:
✔ Ultra-Low Input Compatibility – Reliable extraction even from minimal samples (e.g., 1mL plasma).
✔ High Recovery Rate & Minimal Fragmentation – Proprietary technology preserves short fragments (~150-200bp), ensuring optimal ctDNA/fetal DNA capture.
✔ Automation-Ready – Supports high-throughput processing for clinical and research applications.
✔ Multi-Platform Compatibility – Seamless integration with qPCR, ddPCR, NGS, and other downstream analyses. Applications: Cancer Monitoring – Dynamic tumor burden tracking & treatment response. NIPT – Safe, accurate fetal genetic screening. Transplant Rejection Surveillance – Donor-derived cfDNA (dd-cfDNA) detection. Purer cfDNA, Stronger Diagnostics —Orsin Medical Technology, Powering Precision Medicine.
Parameter | Orsin Technology | Industry Standard (Typical) |
---|---|---|
Input Volume | 0.5-2 mL plasma (ultra-low input compatible) | 3-10 mL plasma |
Yield Efficiency | >85% recovery (50-200bp fragments) | 60-75% recovery |
Fragment Retention | Optimized for 50-300bp (critical for ctDNA) | Bias toward >150bp |
Process Time | 30 min (semi-automated) / 96 samples in 2h | 2-4 hours (manual) |
Inhibitor Removal | PCR/NGS-compatible (A260/A280: 1.8-2.0) | Frequent heparin/hemoglobin interference |
Feature | Orsin Advantage | Common Limitations Elsewhere |
---|---|---|
Short-DNA Capture | Proprietary silica beads + size-selection | Loss of <100bp ctDNA |
Automation | Fully compatible with KingFisher/Hamilton | Manual column-based kits |
Multiplexing | Simultaneous extraction of cfDNA+exosomes* | cfDNA-only isolation |
Cost per Sample | ~$15 (high-throughput) | $20-50 (competitor kits) |
NGS: <5% adapter dimers (vs 15-30% in standard kits)
ddPCR: CV <3% for low-abundance mutations (0.1% VAF)
Methylation Analysis: Preserves epigenetic signatures
LoD: 0.01% mutant allele frequency (MAF) in 5ng cfDNA
Reproducibility: 98% concordance in 500+ clinical samples
At Orsin Medical Technology, we combine cutting-edge innovation with clinical practicality to redefine liquid biopsy standards. Our cfDNA solutions are:
Validated – Rigorously tested in CAP/CLIA environments
Scalable – From research to high-volume clinical labs
Evolving – Continuous optimization for emerging biomarkers (e.g., fragmentomics, methylation patterns)
Partner with us to unlock the full potential of liquid biopsy.
Contact our technical team for assay validation protocols & application-specific protocols.